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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303814Generated: November 2, 2026

Triethylamine → HCID 18461475, compound

https://huagongshe.com/reaction/2303814

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantDiethyl cyanophosphonateHCID 76257—
Reactant2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acidHCID 11323485—
ReactantHCID 18461251HCID 18461251—
SolventTetrahydrofuranHCID 8028—
ProductHCID 18461475HCID 1846147590.4%

Reaction Steps

In a similar manner to that described in Example (2-1), a reaction was carried out using t-butyl N-[2-amino-5-(4-benzylphenoxy)phenyl]-N-methylcarbamate (0.61 g), 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid (0.51 g), diethyl cyanophosphonate (0.29 g), triethylamine (0.18 g) and anhydrous tetrahydrofuran (10 ml) and the reaction mixture was purified to give the desired product (0.91 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432993B1
Source datasetuspto-grants-2002_08
ORD IDord-eda1ef7fd53f4b849f090abd4bc90812
Source noteuspto-grants-2002_08