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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303818Generated: November 2, 2026

Triethylamine → HCID 178486014, compound

https://huagongshe.com/reaction/2303818

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantDiethyl cyanophosphonateHCID 76257—
Reactant2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acidHCID 11323485—
ReactantHCID 178486013HCID 178486013—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178486014HCID 17848601489.5%

Reaction Steps

In a similar manner to that described in Example (2-1), a reaction was carried out using t-butyl N-{2-amino-5-[4-(tetrazol-5-yl)phenoxy]phenyl}-N-methylcarbamate (0.69 g), 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid (0.37 g), diethyl cyanophosphonate (0.21 g), triethylamine (0.13 g) and anhydrous tetrahydrofuran (30 ml) and the reaction mixture was purified to give the desired product (0.76 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432993B1
Source datasetuspto-grants-2002_08
ORD IDord-82ceca6c1eb44f439f061c1bf83718c1
Source noteuspto-grants-2002_08