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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303821Generated: October 29, 2026

Triethylamine → HCID 18461435, compound

https://huagongshe.com/reaction/2303821

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantDiethyl cyanophosphonateHCID 76257—
Reactant2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acidHCID 11323485—
ReactantHCID 18461278HCID 18461278—
SolventTetrahydrofuranHCID 8028—
ProductHCID 18461435HCID 1846143599.8%

Reaction Steps

In a similar manner to that described in Example (2-1), a reaction was carried out using t-butyl N-[2-amino-5-(2,5-di-t-butyl-4-hydroxyphenoxy)phenyl]-N-methylcarbamate (0.71 g), 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid (0.68 g), diethyl cyanophosphonate (0.39 g), triethylamine (0.24 g) and anhydrous tetrahydrofuran (30 ml) and the reaction mixture was purified to give the desired product (1.13 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432993B1
Source datasetuspto-grants-2002_08
ORD IDord-8e96f4cd396148428034614cfc091535
Source noteuspto-grants-2002_08