HuagongsheHuagongshe Chemistry Print Report · For research reference only
Monobenzone → t-Butyl N-[5-(4-benzyloxyphenoxy)-2-nitrophenyl]-N-methylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Monobenzone | HCID 7638 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | tert-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate | HCID 15544598 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | t-Butyl N-[5-(4-benzyloxyphenoxy)-2-nitrophenyl]-N-methylcarbamate | HCID 18461365 | 92.5% |
Reaction Steps
By using 1.60 g of 4-benzyloxyphenol, 2.29 g of t-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate, 0.35 g of sodium hydride (55% by weight) and 20 ml of anhydrous N,N-dimethylformamide, reaction and purification were carried out in a similar manner to that described in Reference Example 6, whereby 3.33 g of the title compound were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432993B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-1a146cedd7614fdda31ef0b66c85574a |
| Source note | uspto-grants-2002_08 |