HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 18461370, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-Benzyloxyphenol | HCID 80459 | — |
| Reactant | tert-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate | HCID 15544598 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18461370 | HCID 18461370 | 92.5% |
Reaction Steps
In a similar manner to that described in Reference Example 6, a reaction was carried out using 2-benzyloxyphenol (2.00 g), t-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate (2.87 g), sodium hydride (55 wt. %, 0.44 g) and anhydrous N,N-dimethylformamide (20 ml) and the reaction mixture was purified to give the title compound (4.16 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432993B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-e9481ee9a11243569030b7d7a895aff1 |
| Source note | uspto-grants-2002_08 |