4-Phenoxyphenol → t-Butyl N-methyl-N-[2-nitro-5-(4-phenoxyphenoxy)phenyl]carbamate

Participants

Reaction Steps

In a similar manner to that described in Reference Example 6, a reaction was carried out using 4-phenoxyphenol (4.0 g), t-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate (5.8 g), sodium hydride (55 wt. %, 1.1 g) and anhydrous N,N-dimethylformamide (35 ml) and the reaction mixture was purified to give the title compound (8.6 g).

Provenance & Evidence