HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 18461289, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-Mercaptophenol | HCID 240147 | — |
| Reactant | tert-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate | HCID 15544598 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18461289 | HCID 18461289 | 76.1% |
Reaction Steps
In a similar manner to that described in Reference Example 6, a reaction was carried out using 4-hydroxythiophenol (1.26 g), t-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate (2.87 g), sodium hydride (55 wt. %, 0.87 g) and anhydrous N,N-dimethylformamide (20 ml) and the reaction mixture was purified to give the title compound (2.86 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432993B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-bd87ffce721a47ef8dbb6411dd5b77a5 |
| Source note | uspto-grants-2002_08 |