Sodium hydride → t-butyl N-[5-(4-hydroxy-2,5-dimethylphenoxy)-2-nitrophenyl]-N-methylcarbamate

Participants

Reaction Steps

In a similar manner to that described in Reference Example 6, a reaction was carried out using 2,5-dimethylhydroquinone (1.38 g), t-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate (2.87 g), sodium hydride (55 wt. %, 0.87 g) and anhydrous N,N-dimethylformamide (20 ml) and the reaction mixture was purified to give the title compound (1.72 g).

Provenance & Evidence