HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenol → HCID 18461286, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenol | HCID 13019 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | tert-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate | HCID 15544598 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18461286 | HCID 18461286 | 57% |
Reaction Steps
In a similar manner to that described in Reference Example 6, a reaction was carried out using 4-cyanophenol (5.1 g), t-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate (11.5 g), sodium hydride (55 wt. %, 1.19 g) and anhydrous N,N-dimethylformamide/anhydrous tetrahydrofuran=5/3 (80 ml) and the reaction mixture was purified to give the title compound (8.45 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432993B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-5a93a2a1ad354d9586b08db0d91cdcdf |
| Source note | uspto-grants-2002_08 |