t-Butyl N-methyl-N-[2-nitro-5-(3-phenylphenoxy)phenyl]carbamate → t-Butyl N-[2-amino-5-(3-phenylphenoxy)phenyl]-N-methylcarbamate

Participants

Reaction Steps

In a similar manner to that described in Reference Example 7, a reaction was carried out using t-butyl N-[2-nitro-5-(3-phenylphenoxy)phenyl]-N-methylcarbamate (8.7 g), palladium on carbon (10%, 0.69 g) and toluene/methanol=7/3 (100 ml) and the reaction mixture was purified to give the title compound (6.06 g).

Provenance & Evidence