HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 18461287, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Benzyl 3-hydroxyphenyl ether | HCID 138048 | — |
| Reactant | tert-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate | HCID 15544598 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18461287 | HCID 18461287 | 82.7% |
Reaction Steps
In a similar manner to that described in Reference Example 6, a reaction was carried out using 3-benzyloxyphenol (5 g), t-butyl N-(5-chloro-2-nitrophenyl)-N-methylcarbamate (6 g), sodium hydride (55 wt. %, 1.1 g) and anhydrous N,N-dimethylformamide (40 ml) and the reaction mixture was purified to give the title compound (7.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432993B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-d8a530a7e0f543168aff498cfb3de614 |
| Source note | uspto-grants-2002_08 |