HCID 18461382, compound → HCID 18461380, compound

HRID 2303904Notes

Reaction equation

HRID 2303904 reaction equation
[CH3:1][O:2][C:3]1[CH:27]=[CH:26][C:6]([O:7][C:8]2[CH:9]=[CH:10][C:11]([N+:23]([O-])=O)=[C:12]([N:14]([CH3:22])[C:15](=[O:21])[O:16][C:17]([CH3:20])([CH3:19])[CH3:18])[CH:13]=2)=[CH:5][CH:4]=1>[Pd].CO>[NH2:23][C:11]1[CH:10]=[CH:9][C:8]([O:7][C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:27][CH:26]=2)=[CH:13][C:12]=1[N:14]([CH3:22])[C:15](=[O:21])[O:16][C:17]([CH3:18])([CH3:20])[CH3:19]

Participants

4

Reactant 1

HCID 18461382HCID 18461382, compound

Product 1

HCID 18461380HCID 18461380, compoundYield 94.1%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

In a similar manner to that described in Reference Example 7, a reaction was carried out using t-butyl N-[5-(4-methoxyphenoxy)-2-nitrophenyl]-N-methylcarbamate (7.2 g), palladium on carbon (10%, 0.5 g) and methanol (100 ml) and the reaction mixture was purified to give the title compound (6.23 g).

Workup

  1. customthe reaction mixture was purified

Sources & evidence

ORD record
ord-3afb77e5c50f40749b83ee1088234641
Source dataset
uspto-grants-2002_08
Patent number
US06432993B1

Reaction notes

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