HCID 57163122, compound → HCID 18462014, compound

Participants

Reaction Steps

To a solution of the product of step 2 (160 mg) in ethanol (3 ml) and acetic acid (1 ml) were added 10% Pd—C (79 mg) was stirred under hydrogen (under a balloon) at room temperature for 24 hour. The mixture was filtered through the celite and distilled off under reduced pressure. The residue was purified by preparative thin layer chromatography eluting with ethyl acetate-hexane (1:2) to give 5-(3-bromopropyl)-5,11-dihydro-7-methoxypyrido[2,3-c][1]benzoxepine (48 mg).

Provenance & Evidence