3-Bromobenzaldehyde → 4-(3-Bromophenyl)butan-1-ol

HRID 2303935Notes

Reaction equation

HRID 2303935 reaction equation
BrC1C=C(C=CC=1)C=O.[Br-].C(CC[P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)(O)=O.[Br:35][C:36]1[CH:37]=[C:38]([CH:42]=[CH:43][CH2:44][C:45](O)=[O:46])[CH:39]=[CH:40][CH:41]=1>>[Br:35][C:36]1[CH:37]=[C:38]([CH2:42][CH2:43][CH2:44][CH2:45][OH:46])[CH:39]=[CH:40][CH:41]=1

Participants

4

Reactant 3

HCID 765833-BromobenzaldehydeHCID 2733850(2-Carboxyethyl)triphenylphosphonium bromideHCID 53882333HCID 53882333, compound

Product 1

HCID 218954894-(3-Bromophenyl)butan-1-ol

Procedure

3-bromobenzaldehyde and 2-carboxyethyltriphenylphosphonium bromide were reacted to synthesize 4-(3-bromophenyl)-3-butenoic acid, then this compound was esterified and then reduced to synthesize the desired compound.

Sources & evidence

ORD record
ord-14c6e19843a54931a10858fe86aa2c57
Source dataset
uspto-grants-2002_08
Patent number
US06433167B1

Reaction notes

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