HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dicyanobenzene → p-Cyanobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dicyanobenzene | HCID 12172 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | p-Cyanobenzamide | HCID 76427 | 62.3% |
Reaction Steps
Terephthalonitrile (12.8 g, 0.1 mol) and methanol (170.1 g) were mixed, and the resultant mixture was heated to 64° C. with stirring. To the mixture, a 20% aqueous solution of sodium hydroxide (12 g) was added over six hours. Liquid chromatographic analysis revealed the reaction mixture contained 9.1 g of p-cyanobenzamide (yield 62%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06433211B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-def75b4f255d4d9fb0f8b28170b05e4b |
| Source note | uspto-grants-2002_08 |