HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dicyanobenzene → p-Cyanobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dicyanobenzene | HCID 12172 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | p-Cyanobenzamide | HCID 76427 | 68% |
Reaction Steps
Terephthalonitrile (12.8 g, 0.1 mol) and n-butanol (243.2 g) were mixed, and the resultant mixture was heated to 80° C. with stirring. To the mixture, a 20% aqueous solution of sodium hydroxide (4 g) was added over three hours. Liquid chromatographic analysis revealed the reaction mixture contained 9.9 g of p-cyanobenzamide (yield 68%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06433211B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-c7c6275a08e544e7a9f46c3687c818bc |
| Source note | uspto-grants-2002_08 |