HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dicyanobenzene → p-Cyanobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dicyanobenzene | HCID 12172 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | p-Cyanobenzamide | HCID 76427 | 105.3% |
Reaction Steps
Terephthalonitrile (12.8 g, 0.1 mol) and tert-butanol (243.2 g) were mixed, and the resultant mixture was heated to 80° C. with stirring. To the mixture, a 26% aqueous solution of potassium hydroxide (4.3 g) was added over three hours. Liquid chromatographic analysis revealed the reaction mixture contained 11.8 g of p-cyanobenzamide (yield 81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06433211B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-e0755be07c2943c192733533c251680f |
| Source note | uspto-grants-2002_08 |