HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isophthalonitrile → 3-Cyanobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isophthalonitrile | HCID 12276 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Cyanobenzamide | HCID 76974 | 90% |
Reaction Steps
Isophthalonitrile (12.8 g, 0.1 mol) and methanol (115.2 g) were mixed, and the resultant mixture was heated to 64° C. with stirring. To the mixture, a 20% aqueous solution of sodium hydroxide (10 g) was added over six hours. Liquid chromatographic analysis revealed the reaction mixture contained 13.1 g of m-cyanobenzamide (yield 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06433211B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-1a2ae9c5372c4ac8910d5503f826749b |
| Source note | uspto-grants-2002_08 |