Sodium Hydroxide → HCID 9925815, compound

HRID 2304070Notes

Reaction equation

HRID 2304070 reaction equation
[Cl:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([Cl:10])[C:5]([Cl:11])=[C:4]([C:12]#[N:13])[C:3]=1[Cl:14].[OH-:15].[Na+]>C(O)C>[Cl:1][C:2]1[C:3]([Cl:14])=[C:4]([C:12]#[N:13])[C:5]([Cl:11])=[C:6]([Cl:10])[C:7]=1[C:8]([NH2:9])=[O:15]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 74694p-Phthalodinitrile, tetrachloro-

Product 1

HCID 9925815HCID 9925815, compoundYield 58.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Tetrachloroterephthalonitrile (26.6 g, 0.1 mol) and ethanol (532 g) were mixed, and the resultant mixture was heated to 79° C. with stirring. To the mixture, a 20% aqueous solution of sodium hydroxide (16 g) was added over six hours. Liquid chromatographic analysis revealed the reaction mixture contained 16.5 g of 2,3,5,6-tetrachloro-4-cyanobenzamide (yield 58%).

Sources & evidence

ORD record
ord-406130b63c134689a9c2a0bd5cc10f43
Source dataset
uspto-grants-2002_08
Patent number
US06433211B1

Reaction notes

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