Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Sodium Persulfate | HCID 62655 | — |
| Reactant | Benzonitrile, 3-(aminomethyl)- | HCID 457594 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Catalyst | Ferrous oxide | HCID 449809 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Cyanobenzoic acid | HCID 15875 | 48.3% |
Reaction Steps
A mixture containing m-cyanobenzylamine (13.2 g), acetonitrile (80 g), sodium hydrogencarbonate (76 g), water (500 g), sodium persulfate (95 g), and iron oxide (0.25 g) was stirred for reaction at 80° C. over ten hours. After the precipitated solid was removed through filtration, the pH of the filtrate was adjusted to 4 through addition of sulfuric acid. The precipitated crystals were collected through filtration, washed with water, dried, to thereby obtain 7.1 g of m-cyanobenzoic acid (yield 48%, based on m-cyano-benzylamine). The m-cyanobenzoic acid obtained had a purity of 94%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06433211B1 |
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| Source dataset | uspto-grants-2002_08 |
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| ORD ID | ord-0d09417caa984748917970256032a775 |
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| Source note | uspto-grants-2002_08 |
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