HCID 12019228, compound → HCID 69538606, compound

HRID 2304385Notes

Reaction equation

HRID 2304385 reaction equation
[S:1](=[O:29])(=[O:28])([O:3][C:4]1[CH:21]=[CH:20][C:19]2[C@@H:18]3[C@H:9]([C@H:10]4[C@@:14]([CH2:16][CH2:17]3)([CH3:15])[C@@H:13]([C:22](=[O:27])[NH:23][CH2:24]CC)[CH2:12][CH2:11]4)[CH2:8][CH2:7][C:6]=2[CH:5]=1)[NH2:2].S(=O)(=O)(OC1C=CC2[C@@H]3[C@H]([C@H]4[C@@](CC3)(C)C(C(=O)NC)=CC4)CCC=2C=1)N>>[S:1](=[O:28])(=[O:29])([O:3][C:4]1[CH:21]=[CH:20][C:19]2[C@@H:18]3[C@H:9]([C@H:10]4[C@@:14]([CH2:16][CH2:17]3)([CH3:15])[C@@H:13]([C:22](=[O:27])[NH:23][CH3:24])[CH2:12][CH2:11]4)[CH2:8][CH2:7][C:6]=2[CH:5]=1)[NH2:2]

Participants

3

Reactant 2

HCID 12019228HCID 12019228, compoundHCID 12020532HCID 12020532, compound

Product 1

HCID 69538606HCID 69538606, compound

Procedure

In similar manners to those described for the synthesis of compound 7, compound 29f was prepared from compound 11f. FAB-MS m/z 393 (M+H)+; 1H NMR (270 MHz, DMSO-d6) δ 0.60 (s, 3H, CH3), 2.59 (d, 3H, J=3.6 Hz, NHCH3), 6.96 (d, 1H, J=2.3 Hz, ArH), 7.01 (dd, 1H, J=2.3, 8.6 Hz, ArH), 7.34 (d, 1H, J=8.6 Hz, ArH), 7.29 (m, 1H, NHCH3), 7.87 (s, 2H, NH2).

Sources & evidence

ORD record
ord-c2c5ee1bf9744261a6f65d0d258df00b
Source dataset
uspto-grants-2002_08
Patent number
US06436918B1

Reaction notes

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