HCID 73444864, compound → HCID 18519342, compound

Participants

Reaction Steps

N,N′-dimethyl-2-butene-1,4-diamine dihydrobromide 73 (35 g) dissolved in a mixture of MeOH (600 ml), i-PrOH (50 ml) and water (100 ml) was hydrogenated in the presence of 10% Pd/C (4 g) at 30 psi for 18 h. The reaction mixture was filtered and the filtrate was concentrated to give N,N′-dimethylputrescine dihydrobromide 74 (32 g) as a white solid.

Provenance & Evidence