3-(Trifluoromethyl)aniline → HCID 178509180, compound

Participants

Reaction Steps

This compound was prepared using 119 mg (0.5 mmol) of 2-[(3-trifluoromethylphenyl)-hydrazono]malononitrile, which was derived from 3-(trifluoromethyl)aniline (125 μL, 1.0 mmol) and malononitrile (1.5 mmol) as described in Example 8, and hydrazine hydrate. Precipitate formed in the reaction tube approximately 10 min after the addition of hydrazine hydrate. The resulting solid was isolated by filtration, washed with ethanol, and dried to yield 43 mg (31%) of the title compound as a yellow solid.

Provenance & Evidence