HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-Gly-Phe-Gly-OBzl → N-Boc-glycyl-L-phenylalanyl-glycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-Gly-Phe-Gly-OBzl | HCID 131722860 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-Boc-glycyl-L-phenylalanyl-glycine | HCID 131722861 | 98% |
Reaction Steps
The resulting Boc-Gly-Phe-Gly-OBzl (1.78 g) was dissolved in ethyl acetate (60 ml) and subjected to catalytic reduction for 24 hours in the presence of 5%-Pd-C (1.8 g). The catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to obtain Boc-Gly-Phe-Gly-OH (1.41 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06436912B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-2c94457d5e2c4f0b878f979205e38078 |
| Source note | uspto-grants-2002_08 |