Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 5-(hydroxymethyl)pyridin-2(1H)-one | HCID 12018576 | — |
| Product | 5-Bromomethyl-2-pyridone | HCID 12018577 | — |
Reaction Steps
To 5-hydroxymethyl-2-pyridone (114.9 mg, 0.9 mmol) was added 3.0 ml of 48% hydrobromic acid. The mixture was heated at 100° C. for 20 minutes. The excess hydrobromic acid was then evaporated in vacuo to give the corresponding 5-bromomethyl-2-pyridone. This compound was used without purification. HRMS: m/e, M+found; 186.9626, 7.4% Calc. for C6H6BrNO: 186.9633, −3.9 ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06436972B1 |
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| Source dataset | uspto-grants-2002_08 |
|---|
| ORD ID | ord-82cdd48aea6b476fa372d24e755202a3 |
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| Source note | uspto-grants-2002_08 |
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