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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2304638Generated: November 2, 2026

HCID 23440891, compound → HCID 12992436, compound

https://huagongshe.com/reaction/2304638

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23440891HCID 23440891—
CatalystAcetic AcidHCID 176—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 12992436HCID 1299243663%

Reaction Steps

A solution of 1-{4-(phenylmethoxy)benzyl}-6-methoxy-2-phenyl-1,2,3,4-tetrahydroisoquinoline (0.60 g, 1.38 mmol), palladium (5% wt. on activated carbon, 0.06 g), and glacial acetic acid (3 drops) in ethanol (30 mL) was stirred under hydrogen for 15 hours. The reaction was filtered and concentrated to provide the title compound (0.30 g, 63% yield): ES-MS (m/z) 346 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06436923B1
Source datasetuspto-grants-2002_08
ORD IDord-519365da6abb4126bde047312ffb8736
Source noteuspto-grants-2002_08