Bromine → HCID 178432201, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 0.9 g (6.1 mmol) of 2-methyl-5-aminobenzimidazole in 50 ml of AcOH was added 0.16 ml of Br2 (3.1 mmol) dropwise and resulting reaction mixture was stirred for 1 h at 25° C. Reaction mixture was concentrated in vacuo and purified on silica gel column chromatography (20%) Isopropanol/EtOAC) to yield 0.56 g (2.5 mmol, 41%) of the desired product.

Provenance & Evidence