Trifluoroacetic acid → HCID 22961303, compound

Participants

Reaction Steps

2-[(1R)-1-[N,N′-Bis-Boc-(2R)-2,5-diaminovaleramido]-3-phenylpropyl]-N-(3-quinolyl)-4-oxazolecarboxamide (66 mg) was deprotected with trifluoroacetic acid to afford the title compound (68 mg) as a white powder: 1H NMR (400 MHz, D2O) δ 1.83 (m, 2H), 2.06 (m, 2H), 2.45 (m, 1H), 2.57 (m, 1H), 2.83 (m, 1H), 2.96 (m, 1H), 3.11 (t, J=8.3 Hz, 2H), 4.19 (t, J=6.0 Hz, 1H), 5.22 (t, J=7.4 Hz, 1H), 7.38 (m, 3H), 7.42 (m, 2H), 7.96 (t, J=9.0 Hz, 1H), 8.09 (t, J=9.0 Hz, 1H), 8.23 (m, 2H), 8.60 (s, 1H), 9.11 (s, 1H), and 9.48 (s, 1H).

Provenance & Evidence