HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diphenyl Ether → HCID 178421951, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diphenyl Ether | HCID 7583 | — |
| Reactant | 4-Methyl-2-[(4-methyl-3-oxo-1-penten-1-yl)amino]-5-phenylthiophene-3-carboxylic acid ethyl ester | HCID 70117389 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178421951 | HCID 178421951 | 80.6% |
Reaction Steps
The compound obtained in Example 13 (50 g) and diphenylether (500 ml) were mixed and the ethanol formed as the reaction proceeded was distilled off while continuing the heating under reflux for 4 hours. After allowing to cool followed by distilling diphenylether off under reduced pressure a crude crystal was precipitated and washed with n-hexane to obtain the title compound (35.1 g, 80.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06437132B2 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-55a1f9b92ecb430ca1bb31c79ea9cf1b |
| Source note | uspto-grants-2002_08 |