4,5,6,7-Tetrahydro-1H-benzoimidazole-5-carboxylic acid → HCID 178483878, compound
Reaction equation
[N:1]1[C:5]2[CH2:6][CH2:7][CH:8]([C:10]([OH:12])=O)[CH2:9][C:4]=2[NH:3][CH:2]=1.[Cl:13][C:14]1[CH:15]=[C:16]([CH:23]=[CH:24][CH:25]=1)[O:17][CH2:18][CH2:19][CH2:20][NH:21][CH3:22]>>[ClH:13].[Cl:13][C:14]1[CH:15]=[C:16]([CH:23]=[CH:24][CH:25]=1)[O:17][CH2:18][CH2:19][CH2:20][N:21]([CH3:22])[C:10]([CH:8]1[CH2:7][CH2:6][C:5]2[NH:1][CH:2]=[N:3][C:4]=2[CH2:9]1)=[O:12]Participants
3
Procedure
By a similar procedure as described in Example 65, the title compound was prepared from 4,5,6,7-tetrahydrobenzimidazole-5-carboxylic acid and 3-(3-chlorophenoxy)propylmethylamine.
Sources & evidence
- ORD record
- ord-7d8e7f058e5241d690c0e136ca254c97
- Source dataset
- uspto-grants-2002_08
- Patent number
- US06437147B1
Reaction notes
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