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HRID230495

反应详情

EQUATION

反应方程式

HRID 230495 的结构方程式

REACTANTS

反应物

2
结构：COc1cc(C)ccc1S(=O)(=O)Cl
HCID11345048

2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE

C8H9ClO3S

结构：CC(C)(C)OC(=O)N1CCN(c2ccc(N)c(NS(=O)(=O)c3ccccc3)c2)CC1
HCID22272479

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(C)ccc1S(=O)(=O)Nc1ccc(N2CCNCC2)cc1NS(=O)(=O)c1ccccc1
HCID10279475

未命名化合物

PROCEDURE

实验过程

2-Methoxy-4-methyl-N-[2-[(phenylsulfonyl)amino]-4-(1-piperazinyl)phenyl]benzenesulfonamide was synthesized from N-{2-amino-5-(4-t-butyloxycarbonyl-piperazinyl)-phenyl}benzenesulfonamide and 2-methoxy-4-methylbenzenesulfonylchloride (53 mg, 0.239 mmol) according to general method 3 to give 80 mg of a purple solid. MS (posES-FIA) m/z=Found: 517.2; Calcd 517.15; 1H NMR δ 7.67-7.37 (m, 6H), 7.10-7.04 (m, 2H), 6.97-6.74 (m, 2H), 6.30 (d, 1H), 4.06 (s, 3H), 3.26-3.09 (m, 8H), 2.37 (s, 3H).