4-Nonylphenol → HCID 14122791, compound

Participants

Reaction Conditions

Reaction Steps

To a 1,000 ml autoclave equipped with an ethylene oxide inlet tube, 220 g (0.998 moles) of nonylphenol having a branched mixture of nonyl group and an ortho/para ratio of 1/9 and 0.83 g (8.3 mmoles as sodium hydroxide) of 40% aqueous sodium hydroxide solution were charged. The reaction system was substituted with nitrogen, heated to 120° C., successively evacuated to 50 mmHg, and dehydrated for an hour under reduced pressure. After the dehydration, the reaction system was returned to atmospheric pressure by feeding nitrogen and heated to 150° C. While maintaining the temperature, 440 g (9.99 moles) of ethylene oxide was fed to the reaction system over 8 hours under increased gauge pressure of 0.2 to 0.4 MPa to carry out ethylene oxide addition reaction of nonylphenol. After ethylene oxide charge, the reaction system was further kept at the same temperature for an hour. After cooling the reaction system, the reaction system was neutralized with 0.52 g (8.7 mmoles) of acetic acid to obtain 660 g of nonylphenol ethylene oxide adduct. Nonylphenol ethylene oxide adduct thus obtained had an average ethylene oxide addition mole number of 10.0.

Provenance & Evidence