反应详情

To a solution of (±)-3-{[2-(4,5-diphenyloxazol-2-yl)-2-cyclohexen-1-yl]methyl}phenylamine (110 mg, 0.27 mmol) in methylene chloride (3 ml) was added benzoylisocyanate (0.038 ml, 0.27 mmol) at 5° C., and the mixture was stirred at room temperature for 16 hours. To the mixture was added hexane (9 ml), and the resulting precipitate was collected, washed with hexane to give (±)-1-benzoyl-3-{3-{[2-(4,5-diphenyloxazol-2-yl)-2-cyclohexen-1-yl]methyl}phenyl}urea (114.9 mg, 77%).

1. customthe resulting precipitate was collected
2. washwashed with hexane