Water → HCID 18432356, compound

Participants

Reaction Conditions

Reaction Steps

0.7 g (1.75 mmol) of 1-chloro-2-(8-chloro-4,4-dimethyl-1,1-dioxothiochroman-7-yl)carbonylcyclohex-1-en-3-one is dissolved in 20 ml of tetrahydrofuran, and 0.11 g (1.75 mmol) of ethanethiol and 0.19 g (1.92 mmol) of triethylamine were added dropwise. The mixture was stirred at 25° C. for 2 hours, stirred into water, extracted with ethyl acetate and the organic phases were extracted with 1N hydrochloric acid and dried and the solvent was removed. This gave 0.4 g of beige crystals.

Provenance & Evidence