HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminobenzoic Acid → 4-[(4-Nitrobenzoyl)amino]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminobenzoic Acid | HCID 978 | — |
| Reactant | 4-Nitrobenzoyl chloride | HCID 8502 | — |
| Reactant | Dimethylacetamide | HCID 31374 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-[(4-Nitrobenzoyl)amino]benzoic acid | HCID 459008 | 94% |
Reaction Steps
10 g of 4-nitrobenzoic acid chloride are slowly introduced into 7.4 g of 4-aminobenzoic acid and 36 ml of dimethylacetamide while maintaining the temperature at less than 25° C. After stirring for 24 hours, 50 ml of methylene chloride are added at 10° C. in order to precipitate the desired product. After washing with water and drying, 14.5 g of product are isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06440956B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-593aac21eaea4ef68a1f68549fbcabaa |
| Source note | uspto-grants-2002_08 |