反应详情

22.53 g (92.9 mmol) of di(m-methoxyphenyl)methyl alcohol were dissolved in 200 ml of diethyl ether and, under a nitrogen atmosphere, 28.76 g (138.3 mmol) of thionyl bromide dissolved in 20 ml of diethyl ether were added dropwise. After 6 hours at room temperature, the mixture was poured into ice-water, and the organic phase was separated off, washed with water and saturated NaHCO3 solution, then dried with MgSO4 and concentrated. 27.73 g (97.8%) of crude product were obtained and were immediately reacted further.

1. additionwere added dropwise
2. customthe organic phase was separated off
3. washwashed with water and saturated NaHCO3 solution
4. dry with materialdried with MgSO4
5. concentrationconcentrated