HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68824197, compound → HCID 57762848, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68824197 | HCID 68824197 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 57762848 | HCID 57762848 | 74.6% |
Reaction Steps
0.113 g of Pd/C (10%) is added to a solution of 0.15 g of 3-(4-nitrophenyl)-1H-pyrrolo[3,2-b]pyridine-2-carboxamide in 10 ml of methanol. After stirring at 22° C. for 3.5 hours under 2 bar of hydrogen, the reaction medium is filtered over silica gel and then concentrated under reduced pressure, to give 0.1 g of 3-(4-aminophenyl)-1H-pyrrolo[3,2-b]pyridine-2-carboxamide, the characteristics of which are as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07566736B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-181af24f849f45629cdff8bbaa3132d2 |
| Source note | uspto-grants-2009_07 |