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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 230547Generated: November 1, 2026

HCID 68824197, compound → HCID 57762848, compound

https://huagongshe.com/reaction/230547

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68824197HCID 68824197—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 57762848HCID 5776284874.6%

Reaction Steps

0.113 g of Pd/C (10%) is added to a solution of 0.15 g of 3-(4-nitrophenyl)-1H-pyrrolo[3,2-b]pyridine-2-carboxamide in 10 ml of methanol. After stirring at 22° C. for 3.5 hours under 2 bar of hydrogen, the reaction medium is filtered over silica gel and then concentrated under reduced pressure, to give 0.1 g of 3-(4-aminophenyl)-1H-pyrrolo[3,2-b]pyridine-2-carboxamide, the characteristics of which are as follows:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07566736B2
Source datasetuspto-grants-2009_07
ORD IDord-181af24f849f45629cdff8bbaa3132d2
Source noteuspto-grants-2009_07