Ethanolamine → 2-(7-Methyl-2-p-tolyl-quinolin-4-ylamino)-ethanol hydrochloride

HRID 2305486Notes

Reaction equation

HRID 2305486 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([CH3:12])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=2)[CH:3]=1.[CH2:20]([CH2:22][NH2:23])[OH:21]>>[ClH:1].[CH3:12][C:8]1[CH:7]=[C:6]2[C:11]([C:2]([NH:23][CH2:22][CH2:20][OH:21])=[CH:3][C:4]([C:13]3[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=3)=[N:5]2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 184330834-Chloro-7-methyl-2-p-tolyl-quinoline

Product 1

HCID 184330692-(7-Methyl-2-p-tolyl-quinolin-4-ylamino)-ethanol hydrochloride

Procedure

The title compound, m.p. 260-263° C. and MS: m/e=293.3 (M+H+), was prepared from 4-chloro-7-methyl-2-p-tolyl-quinoline and ethanolamine.

Sources & evidence

ORD record
ord-4c66857c162e4672b68010b97a8a326d
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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