1,3-Diamino-2-propanol → HCID 18433118, compound

HRID 2305488Notes

Reaction equation

HRID 2305488 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([N:12]2[CH2:21][CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:13]2)[CH:3]=1.[NH2:22][CH2:23][CH:24]([OH:27])[CH2:25][NH2:26]>>[ClH:1].[NH2:22][CH2:23][CH:24]([OH:27])[CH2:25][NH:26][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([N:12]2[CH2:21][CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:13]2)[CH:3]=1

Participants

3

Reactant 2

HCID 611571,3-Diamino-2-propanolHCID 18433086HCID 18433086, compound

Product 1

HCID 18433118HCID 18433118, compound

Procedure

The title compound, m.p. 265-275° C., MS: m/e=348 (M+), was prepared from 4-chloro-2-(3,4-dihydro-1H-isoquinolin-2-yl)-quinoline and 1,3-diamino-2-propanol.

Sources & evidence

ORD record
ord-c3d38789481a43ecbb15b43f45bb095a
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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