1,3-Diamino-2-propanol → HCID 18432973, compound
Reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)[CH:3]=1.[NH2:22][CH2:23][CH:24]([OH:27])[CH2:25][NH2:26]>>[ClH:1].[NH2:22][CH2:23][CH:24]([OH:27])[CH2:25][NH:26][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)[CH:3]=1Participants
3
Procedure
The title compound, m.p. 190-205° C. and MS: m/e=353 (M+), was prepared from 4-chloro-7-methoxy-2-(4-methoxy-phenyl)-quinoline and 1,3-diamino-2-propanol.
Sources & evidence
- ORD record
- ord-7b29f65b2e1b48e094a1d150be4c3463
- Source dataset
- uspto-grants-2002_08
- Patent number
- US06440995B1
Reaction notes
Loading…