1,3-Diamino-2-propanol → HCID 18433123, compound

HRID 2305497Notes

Reaction equation

HRID 2305497 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=2)[CH:3]=1.[NH2:21][CH2:22][CH:23]([OH:26])[CH2:24][NH2:25]>>[ClH:1].[NH2:21][CH2:22][CH:23]([OH:26])[CH2:24][NH:25][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 611571,3-Diamino-2-propanolHCID 18432961HCID 18432961, compound

Product 1

HCID 18433123HCID 18433123, compound

Procedure

The title compound, m.p. 269-271° C. and MS: m/e=358.1 (M+H+), was prepared from 4-chloro-2-(4-chloro-phenyl)-7-methoxy-quinoline and 1,3-diamino-2-propanol.

Sources & evidence

ORD record
ord-28ca9131f4774c5ba2d60770f82c6a60
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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