1,3-Diamino-2-propanol → HCID 18433066, compound
Reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[C:16]([Cl:21])[CH:15]=2)[CH:3]=1.[NH2:22][CH2:23][CH:24]([OH:27])[CH2:25][NH2:26]>>[ClH:1].[NH2:22][CH2:23][CH:24]([OH:27])[CH2:25][NH:26][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[C:16]([Cl:21])[CH:15]=2)[CH:3]=1Participants
3
Procedure
The title compound, m.p. 230-233° C., and MS: m/e=391 (M+), was prepared from 4-chloro-2-(3,4-dichloro-phenyl)-7-methoxy-quinoline and 1,3-diamino-2-propanol.
Sources & evidence
- ORD record
- ord-2434941c2adb45018af23fc8a8fcaeb6
- Source dataset
- uspto-grants-2002_08
- Patent number
- US06440995B1
Reaction notes
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