Isopropylamine → HCID 9949647, compound

HRID 2305542Notes

Reaction equation

[O:1]1[CH2:3][CH:2]1[CH2:4][O:5][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[N:9]=[C:8]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:7]=1.[CH:22]([NH2:25])([CH3:24])[CH3:23]>>[CH:22]([NH:25][CH2:3][CH:2]([OH:1])[CH2:4][O:5][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[N:9]=[C:8]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:7]=1)([CH3:24])[CH3:23]

Participants

Reactant 2

HCID 6363Isopropylamine

HCID 18432932HCID 18432932, compound

Product 1

HCID 9949647HCID 9949647, compound

Procedure

The title compound, m. p. 109-111° C., MS: m/e=337.2 (M+H+), was prepared from (RS)-4-oxiranylmethoxy-2-phenyl-quinoline and isopropylamine.

Sources & evidence

ORD record: ord-35ba82d145ce4c599f0eebc11bdeb1ba
Source dataset: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06440995B1

Reaction notes

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