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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2305557Generated: October 25, 2026

4-Chloroquinoline → 4-Chloro-2-(2,3-dihydro-benzofuran-5-yl)-quinoline

https://huagongshe.com/reaction/2305557

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroquinolineHCID 69140—
Reactant5-Iodo-2,3-dihydro-1-benzofuranHCID 2736133—
Product4-Chloro-2-(2,3-dihydro-benzofuran-5-yl)-quinolineHCID 18433025—

Reaction Steps

The title compound, m. p. 130-132° C., MS: m/e=281 (M+), was prepared from 4-chloro-quinoline and 5-iodo-2,3-dihydrobenzofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06440995B1
Source datasetuspto-grants-2002_08
ORD IDord-489c03cb8f794f5181898ce2c7ab0027
Source noteuspto-grants-2002_08