4-Chloroquinoline → 4-Chloro-2-chroman-6-yl-quinoline

HRID 2305560Notes

Reaction equation

[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.Br[C:13]1[CH:14]=[C:15]2[C:20](=[CH:21][CH:22]=1)[O:19][CH2:18][CH2:17][CH2:16]2>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:13]2[CH:14]=[C:15]3[C:20](=[CH:21][CH:22]=2)[O:19][CH2:18][CH2:17][CH2:16]3)[CH:3]=1

Participants

Reactant 2

HCID 691404-Chloroquinoline

HCID 108568146-Bromochroman

Product 1

HCID 184329544-Chloro-2-chroman-6-yl-quinoline

Procedure

The title compound, MS: m/e=295 (M+), was prepared from 4-chloro-quinoline and 6-bromo-chroman.

Sources & evidence

ORD record: ord-9f8adb1827a741c4afaca77d5081e556
Source dataset: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06440995B1

Reaction notes

Loading…