HCID 4777860, compound → HCID 68826346, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 540 mg (2.84 mmol) of 6-methoxy-1H-indole-2-carboxamide in 8 ml of pyridine is cooled to 0° C. and a solution of 908 mg (2.84 mmol) of pyridinium tribromide in 6 ml of pyridine is added thereto, dropwise. The reaction medium is stirred at 0° C. for 30 minutes and at ambient temperature for 19 h. 20 ml of ice-cold water is added to the reaction medium. The latter is then stirred at ambient temperature for 1 h and then filtered over sintered glass, to give 538 mg of 3-bromo-6-methoxy-1H-indole-2-carboxamide in the form of a white solid.

Provenance & Evidence