2-Fluoroethyl bromide → 5-(S)-Azidomethyl-3-[4'-(2''-fluoroethyl)thio-3'-fluorophenyl]oxazolidine-2-one

Participants

Reaction Steps

This compound was prepared analogously to the synthesis of 5-(S)-azidomethyl-3-[4′-methylthio-3′-fluorophenyl]oxazolidine-2-one from 1-bromo-2-fluoroethane (0.109 ml, 1.47 mmol) and 5-(S)-azidomethyl-3-[4′-triphenylmethylthio-3′-fluorophenyl]-oxazolidine-2-one (0.500 g, 0.979 mmol). Yield 0.280 g (91%). MS (m/z): [M+H]+=315.

Provenance & Evidence