3,5-Dimethyl-4-hydroxybenzaldehyde → 1-[2-Methyloxy-4-chlorophenyl]-3-[3,5-dimethyl-4-hydroxyphenyl]prop-2-en-1-one

HRID 230576Notes

Reaction equation

HRID 230576 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[C:4]([O:11][CH3:12])[CH:3]=1.[CH3:13][C:14]1[CH:15]=[C:16]([CH:19]=[C:20]([CH3:23])[C:21]=1[OH:22])[CH:17]=O>>[CH3:12][O:11][C:4]1[CH:3]=[C:2]([Cl:1])[CH:7]=[CH:6][C:5]=1[C:8](=[O:10])[CH:9]=[CH:17][C:16]1[CH:19]=[C:20]([CH3:23])[C:21]([OH:22])=[C:14]([CH3:13])[CH:15]=1

Participants

3

Reactant 2

HCID 752223,5-Dimethyl-4-hydroxybenzaldehydeHCID 194294681-(4-Chloro-2-methoxyphenyl)ethan-1-one

Product 1

HCID 685660931-[2-Methyloxy-4-chlorophenyl]-3-[3,5-dimethyl-4-hydroxyphenyl]prop-2-en-1-one

Procedure

This compound was synthesized from 4′-chloro-2′-methoxyacetophenone and 3,5-dimethyl-4-hydroxybenzaldehyde according to general method 1 described earlier.

Sources & evidence

ORD record
ord-66e01da93edf41fa942f91a5b7bcb3c9
Source dataset
uspto-grants-2009_07
Patent number
US07566737B2

Reaction notes

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