Isopropylhydroxylamine → alpha-(3,4-Ethylenedioxyphenyl)-N-isopropylnitrone

HRID 2305784Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2305784
[CH2:1]1[CH2:12][O:11][C:10]2[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][C:3]=2[O:2]1.[CH:13]([NH:16][OH:17])([CH3:15])[CH3:14]>>[CH2:1]1[CH2:12][O:11][C:10]2[CH:9]=[CH:8][C:5]([CH:6]=[N+:16]([CH:13]([CH3:15])[CH3:14])[O-:17])=[CH:4][C:3]=2[O:2]1

Komponenten

3

Edukt 2

HCID 78763IsopropylhydroxylamineHCID 2481272,3-Dihydro-1,4-benzodioxin-6-carbaldehyde

Produkt 1

HCID 85336065alpha-(3,4-Ethylenedioxyphenyl)-N-isopropylnitrone

Versuchsvorschrift

The title compound was prepared according to the procedure described in Example 11 using 3,4-ethylenedioxybenzaldehyde and N-isopropylhydroxylamine. The crude produce was purified by column chromatography over silica gel using ethyl acetate as the eluant. The title compound was isolated in 53% yield as a solid, m.p. 108.8° C. (Rf=0.31 on a silica gel plate using EtOAc as the eluant).

Aufarbeitung

  1. customThe title compound was prepared
  2. customThe crude produce
  3. customwas purified by column chromatography over silica gel

Quellen und Nachweise

ORD-Eintrag
ord-42b02dc9ccfc4c72a6991830cfb7ac4d
Quelldatensatz
uspto-grants-2002_08
Patentnummer
US06441032B1

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