Benzaldehyde, 4-(phenylmethoxy)- → HCID 73444829, compound

Participants

Reaction Steps

A mixture of 4-benzyloxybenzaldehyde, N-tert-butylhydroxylamine and catalytic amount of p-toluenesulfonic acid monohydrate in benzene was refluxed under argon atmosphere with a Dean-Stark trap to remove generated water. The mixture was then rotary evaporated to give a residue which was purified by recrystallization. The title compound was obtained in 89.3% yield as a white powder, m.p. 111.0° C. (Rf=0.66 on a silica gel plate using EtOAc as an eluant).

Provenance & Evidence